1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇
NLG919
CAS: 1402836-58-1
Molecular Formula: C18H22N2O
1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇 - Names and Identifiers
| Name | NLG919 |
| Synonyms | NLG919 CS-820 NLG-919 GDC 0919 IDO INHIBITOR 5-(2-Cyclohexyl-2-hydroxyethyl)-5H-imidazo[5,1-a]isoindole |
| CAS | 1402836-58-1 |
| EINECS | 1592732-453-0 |
1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇 - Physico-chemical Properties
| Molecular Formula | C18H22N2O |
| Molar Mass | 282.38 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 143 - 146°C |
| Boling Point | 524.6±33.0 °C(Predicted) |
| Appearance | Form solid, color White |
| pKa | 14.85±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Physical and Chemical Properties | Bioactive IDO-IN-2 (RG 6078, NLG-919 analog, GDC-0919 analog) is an effective IDO1 pathway inhibitor with IC50 value of 38 nM. |
1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.541 ml | 17.707 ml | 35.413 ml |
| 5 mM | 0.708 ml | 3.541 ml | 7.083 ml |
| 10 mM | 0.354 ml | 1.771 ml | 3.541 ml |
| 5 mM | 0.071 ml | 0.354 ml | 0.708 ml |
Last Update：2024-01-02 23:10:35
1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇 - Nature
| Solubility | Soluble in DMSO (up to 15 mg/ml) |
Last Update：2024-04-10 22:29:15
![1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇](http://res.chembk.com/assets/images/structure/302503.gif)
Supplier List
Spot supply
Product Name: NLG-919 analogue; GDC-0919 analogue Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: NLG-919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: NLG-919 analogue; GDC-0919 analogue Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: NLG-919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: NLG919 Visit Supplier Webpage Request for quotationCAS: 1402836-58-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
1-环己基-2-(5H-咪唑并[5,1-a]异吲哚-5-基)乙醇
专利兰VF(二硫蓝)
2-(2-氯-6-甲基吡啶-3-基)乙酸
Ethyl para-fluorobenzoate
XANTHOSINE DIHYDRATE
(2E)-3-(2-噻吩基)丙烯酸
Phosphorothioic acid O-[2-(tert-butyl)-5-pyrimidinyl] O-ethyl O-(1-methylethyl) ester
2-PHENYL-2-TRIFLUOROMETHYLCYCLOHEXANONE
3-(2-氨基乙基氨基)丙基三甲氧基硅烷
3-BOC-1-甲基-6-氧杂-3-氮杂双环[3.1.0]己烷
专利兰VF(二硫蓝)
2-(2-氯-6-甲基吡啶-3-基)乙酸
Ethyl para-fluorobenzoate
XANTHOSINE DIHYDRATE
(2E)-3-(2-噻吩基)丙烯酸
Phosphorothioic acid O-[2-(tert-butyl)-5-pyrimidinyl] O-ethyl O-(1-methylethyl) ester
2-PHENYL-2-TRIFLUOROMETHYLCYCLOHEXANONE
3-(2-氨基乙基氨基)丙基三甲氧基硅烷
3-BOC-1-甲基-6-氧杂-3-氮杂双环[3.1.0]己烷